Tranexamic acid is a synthetic derivative of the amino acid lysine. It works by helping to reduce the breakdown of blood clots, thus preventing the breakdown of fibrin, which is involved in forming blood clots. As a result, it helps to control and reduce bleeding.
Overview
INCI name : Tranexamic Acid
CAS No. : 1197-18-8
EINECS No. : 214-818-2
Formula : C8H15NO2
Category : API, whiting cosmetics
Tranexamic Acid Properties
| Item | Specification |
| Appearance | White or almost white, crystalline powder |
| Solubility | Freely soluble in water and in glacial acetic acid, practically insoluble in acetone and 96% alcohol |
| Identification | Infrared absorption atlas consistent with the contrast atlas |
| Clarity and color | Solution should clarify and colorless |
| Assay | 99.0% ~ 101.0% |
| PH | 7.0 ~ 8.0 |
| Related substances Liquid chromatography (2.2.29) | Impurity A: ≤0.1% Impurity B: ≤0.2% Any other impurity : ≤0.1% All other impurity : ≤0.2% |
| Chlorides | ≤140ppm |
| Heavy Metals | ≤10ppm |
| Loss on drying | ≤0.5% |
| Sulphated Ash | ≤0.10% |
| Bacterial Count | ≤10CFU/G |
| Mold and Yeast | ≤10CFU/G |
Tranexamic Acid Applications
Skin cosmetics
Replying on its antifibrinolytic properties, Tranexamic Acid is suitable for all kinds of skin cosmetics. Tranexamic Acid can remove pigmentation, whitening and lighten spots such as, pigmentation after sun exposure, dark spots (chloasma, freckles, senile lentils, etc.), sensitive skin, acne and inflammation, postoperative care after laser, pulse light treatment.The main products include cream, lotion, essence, and facial mask.
Control of Bleeding
Tranexamic acid is help to control or prevent excessive bleeding, particularly in situations such as heavy menstrual bleeding, nosebleeds, or bleeding disorders. Tranexamic acid is suitable to women experiencing heavy menstrual bleeding (menorrhagia) to help reduce the amount of blood loss during menstruation.
Surgery
During surgical procedures Tranexamic acid reduces blood loss and the need for blood transfusions. It is often used in orthopedic, cardiac, and trauma surgeries, which minimize bleeding during and after the operation.
Dental Procedures
Dentists uses tranexamic acid to reduce bleeding during dental surgeries or procedures, especially in patients with bleeding disorders or those taking blood-thinning medications.
Trauma
Tranexamic acid has been used in the management of traumatic hemorrhage, which reduces the risk of severe blood loss.
Hemorrhagic Conditions
It has treatment of certain hemorrhagic conditions such as hemophilia and von Willebrand disease.
Postpartum Hemorrhage
Tranexamic acid is sometimes suitable to manage postpartum hemorrhage.
Packaging
25kg/drum
Storage
Store in cool and dry air-flowing area preventing sunlight. Shelf life : five years.
